From Lostpedia
Many characters from Season 1, Season 2, and Season 3 of Lost appear in Lost: Via Domus.
Note: The color blue means the character only appeared in flashbacks.
Original game characters
| Elliott Maslow
| Lost: Via Domus
| A photojournalist who has taken some upsetting pictures in Sydney. After the crash he suffers from amnesia, but needs to find his way home.
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| Lisa Gellhorn
| Lost: Via Domus
| A journalist who haunts Elliot on the island. She used to work with him before he boarded 815, but Elliot does not remember what happened to her.
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| Todd
| "Worth A Thousand Words"
| Todd wanted the fuses from the submerged shark in the station, and so Patrick asked Susan to retrieve them. Note - Character not shown in-game.
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| Susan O.
| "Worth A Thousand Words"
| Was asked by Todd to get the fuses from the submerged shark in the Hydra station. Note - Character not shown in-game.
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Losties
| Michael Dawson
| "Force Majeure", "A New Day"
| Michael is a useful to trade torches with before you enter the caves. Michael is seen chopping and collecting wood in the jungle to build a raft. Michael isn't seen after episode two because he is on the raft.
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| Jin Kwon
| "Force Majeure", "A New Day", "Via Domus"
| Jin is seen on the plane in the first episode. In episode three, Jin is seen in the jungle, but it is unknown why he is there. Later he is on the raft with Michael, Sawyer, and Walt.
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| Vincent
| "Force Majeure"
| Vincent is found in the jungle after the plane crashes. He leads you to the plane wreckage.
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| Redshirts
| "Force Majeure"
| There are several redshirt survivors seen at the crash sight in the first episode. Jack is seen trying to save one of the survivors. There are no redshirts present at the beach camp throughout the rest of the game.
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The Others
| Mikhail Bakunin
| "Whatever It Takes"
| Mikhail appears stationed at the Flame in episode six. While Elliott holds him at gunpoint, an Other shoots Elliott with a toxic dart, knocking him out.
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The DHARMA Initiative
| Desmond Hume
| "Fourty-Two"
| Desmond is briefly seen on your way to the Swan. Desmond is running away from the Swan before the countdown reaches zero.
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The Hanso Foundation
Mentioned characters
The following characters were mentioned but not seen: